Basic information of CCL20 :
| Official Symbol of Gene | CCL20 |
| Species | Homo sapiens |
| Entrez Gene ID | 6364 |
| Official Full Name | C-C motif chemokine ligand 20 |
| Also known as | CKb4; LARC; ST38; MIP3A; Exodus; MIP-3a; SCYA20; MIP-3-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000115009 MIM:601960; AllianceGenome:HGNC:10619 |
| Map Location | 2q36.3 |
| Variation Type | SNP |
| refSNP ID | rs6749704 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS,PPMS,SPMS |
| Population | N/A |
| Sample Size | 135 MS patients and 135 healthy subjects |
Literature information of multiple sclerosis :
| Pubmed ID | 24395091 |
| Year | 2013 |
| Title | Higher Circulating Levels of Chemokine CCL20 in Patients with Multiple Sclerosis: Evaluation of the Influences of Chemokine Gene Polymorphism, Gender, Treatment and Disease Pattern |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | higher levels of CCL20 in patients that represent that the chemokine may play an important role in the pathogenesis ofMS |
| Mechanism/Pathway | The rs6749704 polymorphismwas an associated SPMS pattern. The levels of CCL20 were not influenced by gender, disease pattern and treatment. |
