Basic information of TNFSF10 :
| Official Symbol of Gene | TNFSF10 |
| Species | Homo sapiens |
| Entrez Gene ID | 8743 |
| Official Full Name | TNF superfamily member 10 |
| Also known as | TL2; APO2L; CD253; TANCR; TRAIL; Apo-2L; TNLG6A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000121858 MIM:603598; AllianceGenome:HGNC:11925 |
| Map Location | 3q26.31 |
| Variation Type | SNP |
| refSNP ID | rs11545817 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | RT-qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Spanish |
| Sample Size | 509 MS patients+226 MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 23658636 |
| Year | 2013 |
| Title | Candidate Gene Study of TRAILand TRAILReceptors: Association with Response to Interferon Beta Therapy in Multiple Sclerosis Patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | These findings show a role for TRAILR-2 gene variations in the clinical outcome of IFN beta therapy that might have relevance as a biomarker to predict the response to IFN beta in MS. |
| Mechanism/Pathway | death signal |
