Basic information of SOCS1 :
| Official Symbol of Gene | SOCS1 |
| Species | Homo sapiens |
| Entrez Gene ID | 8651 |
| Official Full Name | suppressor of cytokine signaling 1 |
| Also known as | JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; TIP-3; AISIMD; SOCS-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000185338 MIM:603597; AllianceGenome:HGNC:19383 |
| Map Location | 16p13.13 |
| Variation Type | SNP |
| refSNP ID | rs243324 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | Taqman |
| Disease | MS |
| Disease subtype | N/A |
| Population | Spanish |
| Sample Size | 3919 MS patients and 4003 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 21716315 |
| Year | 2011 |
| Title | A cytokine gene screen uncovers SOCS1 as genetic risk factor for multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The SOCS1 rs243324 variant was validated as risk factor for MS |
| Mechanism/Pathway | The association with SOCS1 appears independent from the chr16MS risk locus CLEC16A |
