Basic information of IL2RA :
| Official Symbol of Gene | IL2RA |
| Species | Homo sapiens |
| Entrez Gene ID | 3559 |
| Official Full Name | interleukin 2 receptor subunit alpha |
| Also known as | p55; CD25; IL2R; IMD41; TCGFR; IDDM10 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008 |
| Map Location | 10p15.1 |
| Variation Type | SNP |
| refSNP ID | rs2104286 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMC |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 64 |
Literature information of multiple sclerosis :
| Pubmed ID | 34386002 |
| Year | 2021 |
| Title | IL2RA Methylation and Gene Expression in Relation to the Multiple Sclerosis-Associated Gene Variant rs2104286 and Soluble IL-2Ra in CD8+ T Cells |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We have identified allele specific methylation of the CpG-site located in intron 1 that is perturbed by the rs2104286 SNP in CD8+ T cells from genotype-selected healthy subjects (HS). |
| Mechanism/Pathway | N/A |
