Basic information of VAV1 :
| Official Symbol of Gene | VAV1 |
| Species | Homo sapiens |
| Entrez Gene ID | 7409 |
| Official Full Name | vav guanine nucleotide exchange factor 1 |
| Also known as | VAV |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000141968 MIM:164875; AllianceGenome:HGNC:12657 |
| Map Location | 19p13.3 |
| Variation Type | SNP |
| refSNP ID | rs2546133-rs2617822 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | We used TAGGER in Haploview version 3.32 (49) and ENTROPY as implemented in Marker software for identifying tSNPs |
| Disease | MS |
| Disease subtype | N/A |
| Population | Sweden or other Nordic countries |
| Sample Size | 12,735 individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 20368159 |
| Year | 2009 |
| Title | A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | VAV1 plays a central role in controlling central nervous system immunemediated disease and proinflammatory cytokine production critical for disease pathogenesis. |
| Mechanism/Pathway | N/A |
