Basic information of CCL22 :
| Official Symbol of Gene | CCL22 |
| Species | Homo sapiens |
| Entrez Gene ID | 10621 |
| Official Full Name | C-C motif chemokine ligand 22 |
| Also known as | MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000102962 MIM:602957; AllianceGenome:HGNC:10621 |
| Map Location | 16q21 |
| Variation Type | SNP |
| refSNP ID | rs4359426 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | Taqmanã€PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Italian population |
| Sample Size | 370 MS cases and 380 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 17967467 |
| Year | 2007 |
| Title | Gender-specific influence of the chromosome 16 chemokine gene cluster on the susceptibility to Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | A trend towards a decreased allelic frequency of the A allele of the CCL22 C/A SNP as well as of the T allele of the CCL17 C/T SNP was found in patients compared with controls |
| Mechanism/Pathway | the presence of theAThaplotype in chromosome 16 chemokine cluster is likely toconfer a decreased risk of developing MS |
