Basic information of FCRL3 :
| Official Symbol of Gene | FCRL3 |
| Species | Homo sapiens |
| Entrez Gene ID | 18506 |
| Official Full Name | Fc receptor like 3 |
| Also known as | MAIA; FCRH3; IFGP3; IRTA3; SPAP2; CD307c |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000160856 MIM:606510; AllianceGenome:HGNC:18506 |
| Map Location | 1q23.1 |
| Variation Type | A functional promoter polymorphism |
| refSNP ID | -169 T/C |
Sample information of multiple sclerosis:
| Detected Sample | venous blood |
| Sample Detail | N/A |
| Detected Method | TaqMan MGB |
| Disease | MS |
| Disease subtype | N/A |
| Population | Hispanic population |
| Sample Size | 94 MS cases and 160 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 17617473 |
| Year | 2007 |
| Title | FcRL3 and multiple sclerosis pathogenesis: role in autoimmunity? |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | An increased susceptibility associated to the -169 T allele was found when MS patients and controls were compared |
| Mechanism/Pathway | FcRL3 has been shown to regulate gene expression and to play a role in several autoimmune diseases |
