Basic information of CD58 :
| Official Symbol of Gene | CD58 |
| Species | Homo sapiens |
| Entrez Gene ID | 965 |
| Official Full Name | CD58 molecule |
| Also known as | ag3; LFA3; LFA-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000116815 MIM:153420; AllianceGenome:HGNC:1688 |
| Map Location | 1p13.1 |
| Variation Type | SNP |
| refSNP ID | rs1335532 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | real-time PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Malaysia |
| Sample Size | 27 multiple sclerosis patients, and compared with 58 age- and gender matched healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 32257069 |
| Year | 2019 |
| Title | Association of CD58 polymorphism and multiple sclerosis in Malaysia: a pilot study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Association (allelic model) between multiple sclerosis and CD58 gene polymorphism alleles rs12044852 (p=0.410), rs2300747 (p=0.881) and rs1335532 (p=0.407) were indistinct. |
| Mechanism/Pathway | CD58 gene is located on chromosome one and it encodes a member of the T lymphocytes CD2 protein ligand |
