Basic information of CD40 :
| Official Symbol of Gene | CD40 |
| Species | Homo sapiens |
| Entrez Gene ID | 11919 |
| Official Full Name | CD40 molecule |
| Also known as | p50; Bp50; CDW40; TNFRSF5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000101017 MIM:109535; AllianceGenome:HGNC:11919 |
| Map Location | 20q13.12 |
| Variation Type | SNP |
| refSNP ID | rs1883832 |
Sample information of multiple sclerosis:
| Detected Sample | venous blood |
| Sample Detail | N/A |
| Detected Method | Genomic DNA Extraction and SNV Analysis |
| Disease | MS |
| Disease subtype | N/A |
| Population | Polish population |
| Sample Size | 94 MS cases and 160 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 33224992 |
| Year | 2020 |
| Title | Some Common SNPs of the T-Cell Homeostasis-Related Genes Are Associated with Multiple Sclerosis, but Not with the Clinical Manifestations of the Disease, in the Polish Population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our analysis of the rs1883832 polymorphisms in the CD40 gene did not show any significant differences in the homozygous genotypes and allele frequencies between the studied groups |
| Mechanism/Pathway | N/A |
