Basic information of APOE :

Official Symbol of Gene	APOE
Species	Homo sapiens
Entrez Gene ID	613
Official Full Name	apolipoprotein E
Also known as	AD2; LPG; APO-E; ApoE4; LDLCQ5
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613
Map Location	19q13.32
Variation Type	Gene polymorphisms
refSNP ID	158R/C

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	Ethnical Tatars population
Sample Size	120 MS cases and 263 controls

Literature information of multiple sclerosis :

Pubmed ID	18664147
Year	2008
Title	[Analysis of the association of allelic variants of apolypoprotein E and interleukin 1 beta genes with multiple sclerosis in ethnic Tatars]

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	Thus, our results show that APOE gene polymor-phism is associated with the risk of MS development inethnic Tatars
Mechanism/Pathway	A combined effect of APOE and IL1B allelic variants has been discovered indicating the increased risk of the disease development in the carriers of APOE*4 and IL1B*T/*T alleles