Basic information of IL1B :
| Official Symbol of Gene | IL1B |
| Species | Homo sapiens |
| Entrez Gene ID | 5992 |
| Official Full Name | interleukin 1 beta |
| Also known as | IL-1; IL1F2; IL1beta; IL1-BETA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992 |
| Map Location | 2q14.1 |
| Variation Type | Gene polymorphisms |
| refSNP ID | –511T/C |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Ethnical Tatars population |
| Sample Size | 120 MS cases and 263 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 18664147 |
| Year | 2008 |
| Title | [Analysis of the association of allelic variants of apolypoprotein E and interleukin 1 beta genes with multiple sclerosis in ethnic Tatars] |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Further-more, our data suggest the importance of –511T/C poly-morphism of IL1B gene in the predisposition for theMS development |
| Mechanism/Pathway | A combined effect of APOE and IL1B allelic variants has been discovered indicating the increased risk of the disease development in the carriers of APOE*4 and IL1B*T/*T alleles |
