Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 4948 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | SNP |
| refSNP ID | rs3135388 |
Sample information of multiple sclerosis:
| Detected Sample | venous blood |
| Sample Detail | N/A |
| Detected Method | Affymetrix GeneChip Mapping 250K |
| Disease | MS |
| Disease subtype | N/A |
| Population | Dutch population |
| Sample Size | 46 MS cases and 194 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 18401352 |
| Year | 2008 |
| Title | EVI5 is a risk gene for multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The HLA-DRB1 surrogate SNP (rs3135388) was significantly associated with MS in this study |
| Mechanism/Pathway | A possible explanation for this may have been the lack of power in the initial study on this smallpopulation |
