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Basic information of EVI5 :

Official Symbol of Gene EVI5
Species Homo sapiens
Entrez Gene ID 3501
Official Full Name ecotropic viral integration site 5
Also known as NB4S; EVI-5
Gene Type protein coding
dbXrefs Ensembl:ENSG00000067208 MIM:602942; AllianceGenome:HGNC:3501
Map Location 1p22.1
Variation Type SNP
refSNP ID rs6680578

Sample information of multiple sclerosis:

Detected Sample venous blood
Sample Detail N/A
Detected Method Affymetrix GeneChip Mapping 250K
Disease MS
Disease subtype N/A
Population Dutch population
Sample Size 46 MS cases and 194 controls

Literature information of multiple sclerosis :

Pubmed ID 18401352
Year 2008
Title EVI5 is a risk gene for multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result Furthermore, two SNPs, both on chromosome 1,located in the EVI5 (ecotropic viral integration site 5) gene gave significant P-values in our replication study:rs10735781 (P0.01, OR2.01, 95% CI 1.19–3.39) andrs6680578 (P0.01, OR1.9, 95% CI 1.16–3.11).
Mechanism/Pathway It is still not clear whether thecausal allele acts through EVI5 itself.