Basic information of APOE :
| Official Symbol of Gene | APOE |
| Species | Homo sapiens |
| Entrez Gene ID | 613 |
| Official Full Name | apolipoprotein E |
| Also known as | AD2; LPG; APO-E; ApoE4; LDLCQ5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613 |
| Map Location | 19q13.32 |
| Variation Type | Alleles |
| refSNP ID | ε3/ε3 |
Sample information of multiple sclerosis:
| Detected Sample | venous blood |
| Sample Detail | N/A |
| Detected Method | Hixon and Vernier |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 1318 MS cases |
Literature information of multiple sclerosis :
| Pubmed ID | 10864599 |
| Year | 2000 |
| Title | Apolipoprotein E genotype related differences in brain lesions of multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Comparison between carriers of at least one ε4 allele to the remainder of the study population confirmed a trend towards a higher T2-LL (15.1 (SD 13.7) v 10.4 (SD 9.2) cm3, p=0.24) and a significantly greater T1-LL (2.4 (SD 3.2) v 1.3 (SD 2.8) cm3, p=0.044) and black hole ratio (13.3 (SD 11.8)v 8.3 (SD 12.5)%, p=0.024) in ε4 patients (figure A–C). |
| Mechanism/Pathway | N/A |
