Basic information of HLA-C :

Official Symbol of Gene	HLA-C
Species	Homo sapiens
Entrez Gene ID	3107
Official Full Name	major histocompatibility complex, class I, C
Also known as	MHC; HLAC; HLC-C; D6S204; PSORS1; HLA-JY3
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000204525 MIM:142840; AllianceGenome:HGNC:4933
Map Location	N/A
Variation Type	genotype
refSNP ID	Cw3

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	peripheral blood leukocytes
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	Japanese
Sample Size	44 MS patients and 98 controls

Literature information of multiple sclerosis :

Pubmed ID	1286977
Year	1992
Title	HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	We found significant associations with HLA-Cw3 (p -- 0.002, Pc = 0.012, RR = 3.2), DR2 (p = 0.007, RR = 2.6), and DQBI*0602 (p = 0.04, RR = 4.0) in Japanese patients for the first time.
Mechanism/Pathway	These results suggest that MS susceptibility may result from polygenic influences and from the presence of environmental factors.