Basic information of VEGFA :
| Official Symbol of Gene | VEGFA |
| Species | Homo sapiens |
| Entrez Gene ID | 12680 |
| Official Full Name | vascular endothelial growth factor A |
| Also known as | VPF; VEGF; MVCD1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000112715 MIM:192240; AllianceGenome:HGNC:12680 |
| Map Location | 6p21.1 |
| Variation Type | SNP |
| refSNP ID | rs3025039 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 400 MS cases and 400 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 28401369 |
| Year | 2017 |
| Title | The Importance of VEGF-KDR Signaling Pathway Genes should Not Be Ignored When the Risk of Developing Multiple Sclerosis is Taken into Consideration |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | VEGF 936C > T showed an association with patients in a recessive model |
| Mechanism/Pathway | VEGF and KDR pathway trigger the process of angiogenesis as well as inflammation, which contributes to the development and progression of demyelinating lesions in multiple sclerosis |
