Basic information of VDR :
| Official Symbol of Gene | VDR |
| Species | Homo sapiens |
| Entrez Gene ID | 12679 |
| Official Full Name | vitamin D receptor |
| Also known as | NR1I1; PPP1R163 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111424 MIM:601769; AllianceGenome:HGNC:12679 |
| Map Location | 12q13.11 |
| Variation Type | Gene polymorphisms |
| refSNP ID | BsmI |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Slovak population |
| Sample Size | 270 MS cases and 303 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 27338176 |
| Year | 2016 |
| Title | ApaI, BsmI and TaqI VDR gene polymorphisms in association with multiple sclerosis in Slovaks |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | our data suggest that VDR gene polymorphisms ApaI, BsmI and TaqI are not useful in the prediction of disease disability progression rate in MS in Slovaks |
| Mechanism/Pathway | Vitamin D acts through vitamin D receptor (VDR) and has promising beneficial effects in the development and progression of multiple sclerosis |
