Basic information of PLXNA3 :
| Official Symbol of Gene | PLXNA3 |
| Species | Homo sapiens |
| Entrez Gene ID | 9101 |
| Official Full Name | plexin A3 |
| Also known as | 6.3; PLXN3; PLXN4; XAP-6; HSSEXGENE |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000130827 MIM:300022; AllianceGenome:HGNC:9101 |
| Map Location | Xq28 |
| Variation Type | SNP |
| refSNP ID | rs5945430 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | TaqMan PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 218 MS cases |
Literature information of multiple sclerosis :
| Pubmed ID | 28536997 |
| Year | 2017 |
| Title | PLXNA3 Variant rs5945430 is Associated with Severe Clinical Course in Male Multiple Sclerosis Patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Genotyping of 187 MS patients for rs5945430 confirmed the association of rs5945430G with increased disease severity in MS males |
| Mechanism/Pathway | PLXNA3 rs5945430G is associated with increased disease severity in MS male patients |
