Basic information of CD58 :
| Official Symbol of Gene | CD58 |
| Species | Homo sapiens |
| Entrez Gene ID | 1688 |
| Official Full Name | CD58 molecule |
| Also known as | ag3; LFA3; LFA-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000116815 MIM:153420; AllianceGenome:HGNC:1688 |
| Map Location | 1p13.1 |
| Variation Type | SNP |
| refSNP ID | rs2300747 A>G |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iranian population |
| Sample Size | 200 MS cases and 200 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 30128676 |
| Year | 2020 |
| Title | High-resolution melting curve analysis of polymorphisms within CD58, CD226, HLA-G genes and association with multiple sclerosis susceptibility in a subset of Iranian population: a case-control study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Concerning rs2300747 polymorphism on CD58 gene, no significant differences were found between cases and controls |
| Mechanism/Pathway | genome-wide association studies have identified susceptibility of immune-related genes to be involved in MS predisposition |
