Basic information of CYP2R1 :
| Official Symbol of Gene | CYP2R1 |
| Species | Homo sapiens |
| Entrez Gene ID | 20580 |
| Official Full Name | cytochrome P450 family 2 subfamily R member 1 |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000186104 MIM:608713; AllianceGenome:HGNC:20580 |
| Map Location | 11p15.2 |
| Variation Type | SNP |
| refSNP ID | rs10766197 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Mexican population |
| Sample Size | 116 MS cases and 226 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 34977256 |
| Year | 2021 |
| Title | Polymorphisms CYP2R1 rs10766197 and CYP27B1 rs10877012 in Multiple Sclerosis: A Case-Control Study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Carriers of GA + AA genotypes of CYP2R1 rs10766197 had an increased risk of MS |
| Mechanism/Pathway | Low vitamin D levels have been reported to be a risk factor for MS, and genetic variances could be implicated |
