Basic information of HLA-DRB5 :
| Official Symbol of Gene | HLA-DRB5 |
| Species | Homo sapiens |
| Entrez Gene ID | 4953 |
| Official Full Name | major histocompatibility complex, class II, DR beta 5 |
| Also known as | DRB5; HLA-DRB5* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000198502 MIM:604776; AllianceGenome:HGNC:4953 |
| Map Location | 6p21.32 |
| Variation Type | SNP |
| refSNP ID | DRB5*null |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | TaqMan |
| Disease | MS |
| Disease subtype | N/A |
| Population | African Americans |
| Sample Size | 769 MS cases and 742 controls and 124 parents |
Literature information of multiple sclerosis :
| Pubmed ID | 18832704 |
| Year | 2008 |
| Title | Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | the HLA-DRB5*null subjects appear to be at increased risk for developing secondary progressive MS |
| Mechanism/Pathway | MS is associated with the MHC located on chromosome 6p21 |
