Basic information of VEGFA :
| Official Symbol of Gene | VEGFA |
| Species | Homo sapiens |
| Entrez Gene ID | 12680 |
| Official Full Name | vascular endothelial growth factor A |
| Also known as | VPF; VEGF; MVCD1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000112715 MIM:192240; AllianceGenome:HGNC:12680 |
| Map Location | 6p21.1 |
| Variation Type | SNP |
| refSNP ID | rs699947 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 150 MS cases and 150 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 31652374 |
| Year | 2019 |
| Title | The evaluation of VEGF and HIF-1α gene polymorphisms and multiple sclerosis susceptibility |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | we showed a significant relationship between the VEGF rs699947 polymorphism and MS in a dominant inheritance model |
| Mechanism/Pathway | VEGF has a major role in neurodegenerative diseases via inflammation |
