Basic information of IL2RA :
| Official Symbol of Gene | IL2RA |
| Species | Homo sapiens |
| Entrez Gene ID | 6008 |
| Official Full Name | interleukin 2 receptor subunit alpha |
| Also known as | p55; CD25; IL2R; IMD41; TCGFR; IDDM10 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008 |
| Map Location | 10p15.1 |
| Variation Type | SNP |
| refSNP ID | rs2104286 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | TaqManã€Affymetrix |
| Disease | MS |
| Disease subtype | N/A |
| Population | white ethnicity |
| Sample Size | 2420 MS cases and 9407 controls and 6425 TID cases |
Literature information of multiple sclerosis :
| Pubmed ID | 19119414 |
| Year | 2009 |
| Title | IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The most associated IL2RA SNP for MS susceptibility is rs2104286 located in intron 1 of IL2RA |
| Mechanism/Pathway | The IL-2/IL-2RA(CD25) pathway plays an essential role in regulating immune responses |
