Basic information of ICAM1 :
| Official Symbol of Gene | ICAM1 |
| Species | Homo sapiens |
| Entrez Gene ID | 5344 |
| Official Full Name | intercellular adhesion molecule 1 |
| Also known as | BB2; CD54; P3.58 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000090339 MIM:147840; AllianceGenome:HGNC:5344 |
| Map Location | 19p13.2 |
| Variation Type | Gene polymorphisms |
| refSNP ID | ICAM1 AA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Finnish population |
| Sample Size | 235 MS cases and 277 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 12590979 |
| Year | 2003 |
| Title | Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | An increased risk for the AA (Lys(469)/Lys(469)) genotype was found in both populations |
| Mechanism/Pathway | sequence variations in the ICAM-1 gene could potentially be responsible for the genetic susceptibility to MS |
