Basic information of IFNAR1 :
| Official Symbol of Gene | IFNAR1 |
| Species | Homo sapiens |
| Entrez Gene ID | 5432 |
| Official Full Name | interferon alpha and beta receptor subunit 1 |
| Also known as | AVP; IFRC; IFNAR; IFNBR; IMD106; IFN-alpha-REC |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000142166 MIM:107450; AllianceGenome:HGNC:5432 |
| Map Location | 21q22.11 |
| Variation Type | SNP |
| refSNP ID | rs2257167 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Spanish population |
| Sample Size | 147 MS cases |
Literature information of multiple sclerosis :
| Pubmed ID | 12618863 |
| Year | 2003 |
| Title | Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | In addition, no significant association was observed of any of the IFNAR gene polymorphisms with susceptibility to MS, as studied by a family-based association analysis |
| Mechanism/Pathway | Interferon beta (IFNbeta) has been shown to decrease clinical relapses, reduce brain disease activity |
