Basic information of NGF :
| Official Symbol of Gene | NGF |
| Species | Homo sapiens |
| Entrez Gene ID | 7808 |
| Official Full Name | nerve growth factor |
| Also known as | NGFB; HSAN5; Beta-NGF |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134259 MIM:162030; AllianceGenome:HGNC:7808 |
| Map Location | 1p13.2 |
| Variation Type | SNP |
| refSNP ID | rs6330 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RRMSã€SPMSã€PPMS |
| Population | N/A |
| Sample Size | 1120 MS cases and 869 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 19063739 |
| Year | 2008 |
| Title | Genomic NGFB variation and multiple sclerosis in a case control study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | rs6330 showed significant association in allele (p = 0.0038; OR = 1.210 (1.063–1.377)) and genotype frequencies (p = 0.0126) when comparing healthy controls and MS patients |
| Mechanism/Pathway | Nerve growth factor β (NGFB) is involved in cell proliferation and survival, and it is a mediator of the immune response |
