Basic information of NGF :
| Official Symbol of Gene | NGF |
| Species | Homo sapiens |
| Entrez Gene ID | 7808 |
| Official Full Name | nerve growth factor |
| Also known as | NGFB; HSAN5; Beta-NGF |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134259 MIM:162030; AllianceGenome:HGNC:7808 |
| Map Location | 1p13.2 |
| Variation Type | SNP |
| refSNP ID | rs6673867 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RRMSã€SPMSã€PPMS |
| Population | N/A |
| Sample Size | 1120 MS cases and 869 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 19063739 |
| Year | 2008 |
| Title | Genomic NGFB variation and multiple sclerosis in a case control study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Analyses of three flanking SNPs, rs3811014, rs17540656 and rs6673867 in the defined subgroups showed no significant association for male MS patients compared to healthy male controls as well as no significant association between female MS patients and female controls |
| Mechanism/Pathway | Nerve growth factor β (NGFB) is involved in cell proliferation and survival, and it is a mediator of the immune response |
