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Basic information of ACE :

Official Symbol of Gene ACE
Species Homo sapiens
Entrez Gene ID 2707
Official Full Name angiotensin I converting enzyme
Also known as DCP; ACE1; DCP1; CD143
Gene Type protein coding
dbXrefs Ensembl:ENSG00000159640 MIM:106180; AllianceGenome:HGNC:2707
Map Location 17q23.3
Variation Type SNP
refSNP ID DD genotype

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Slovenia and Croatia population
Sample Size 313 MS cases and 376 controls

Literature information of multiple sclerosis :

Pubmed ID 17083336
Year 2006
Title Angiotensin-converting enzyme I/D gene polymorphism and risk of multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result DD genotype of ACE gene might contribute to a higher risk of developing MS in men
Mechanism/Pathway the blockade of ACE suppresses the disease itself