Basic information of TNFAIP3 :
| Official Symbol of Gene | TNFAIP3 |
| Species | Homo sapiens |
| Entrez Gene ID | 11896 |
| Official Full Name | TNF alpha induced protein 3 |
| Also known as | A20; AISBL; AIFBL1; OTUD7C; TNFA1P2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000118503 MIM:191163; AllianceGenome:HGNC:11896 |
| Map Location | 6q23.3 |
| Variation Type | SNP |
| refSNP ID | rs6922466 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RT-PCRã€TaqMan PCR |
| Disease | MS |
| Disease subtype | RRMSã€SPMSã€PPMS |
| Population | Caucasian |
| Sample Size | 497 MS cases and 878 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 25684197 |
| Year | 2015 |
| Title | Association of TNFAIP3 and TNFRSF1A variation with multiple sclerosis in a German case-control cohort |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | and rs6922466 did not show association with MS |
| Mechanism/Pathway | evidence is accumulating that polymorphisms in both TNFAIP3 and TNFRSF1A genes play a role in MS pathogenesis |
