Basic information of HFE :
| Official Symbol of Gene | HFE |
| Species | Homo sapiens |
| Entrez Gene ID | 4886 |
| Official Full Name | homeostatic iron regulator |
| Also known as | HH; HFE1; HLA-H; MVCD7; TFQTL2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000010704 MIM:613609; AllianceGenome:HGNC:4886 |
| Map Location | 6p22.2 |
| Variation Type | Gene polymorphisms |
| refSNP ID | H63D |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 373 MS cases and 373 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20586792 |
| Year | 2011 |
| Title | HFE gene polymorphisms and severity in Portuguese patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | No significant association was found between HFE polymorphisms and disease susceptibility |
| Mechanism/Pathway | It has been proposed that HFE gene polymorphisms could have a role in MS |
