Basic information of HLA-DRB3 :
| Official Symbol of Gene | HLA-DRB3 |
| Species | Homo sapiens |
| Entrez Gene ID | 4951 |
| Official Full Name | major histocompatibility complex, class II, DR beta 3 |
| Also known as | DRB3; HLA-DPB1; HLA-DR1B; HLA-DR3B; HLA-DRB3* |
| Gene Type | protein coding |
| dbXrefs | MIM:612735 |
| Map Location | 6p21.3 |
| Variation Type | Gene polymorphisms |
| refSNP ID | DRB3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian population |
| Sample Size | 27 NMOSD cases and 29 MS cases and 28 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 21396892 |
| Year | 2010 |
| Title | HLA-DRB association in neuromyelitis optica is different from that observed in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | DRB3 was overrepresented in NM |
| Mechanism/Pathway | these results indicate that the DRB profile of NMO patients is different from that observed for MS patients, further corroborating the distinction between NMO and MS |
