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Basic information of HLA-DRB5 :

Official Symbol of Gene HLA-DRB5
Species Homo sapiens
Entrez Gene ID 4953
Official Full Name major histocompatibility complex, class II, DR beta 5
Also known as DRB5; HLA-DRB5*
Gene Type protein coding
dbXrefs Ensembl:ENSG00000198502 MIM:604776; AllianceGenome:HGNC:4953
Map Location 6p21.32
Variation Type Gene polymorphisms
refSNP ID DRB5*0101

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Caucasian population
Sample Size 27 NMOSD cases and 29 MS cases and 28 controls

Literature information of multiple sclerosis :

Pubmed ID 21396892
Year 2010
Title HLA-DRB association in neuromyelitis optica is different from that observed in multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result DRB5 overrepresented in MS patients
Mechanism/Pathway these results indicate that the DRB profile of NMO patients is different from that observed for MS patients, further corroborating the distinction between NMO and MS