Basic information of AGER :
| Official Symbol of Gene | AGER |
| Species | Homo sapiens |
| Entrez Gene ID | 320 |
| Official Full Name | advanced glycosylation end-product specific receptor |
| Also known as | RAGE; sRAGE; SCARJ1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000204305 MIM:600214; AllianceGenome:HGNC:320 |
| Map Location | 6p21.32 |
| Variation Type | SNP |
| refSNP ID | rs1800624 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 64 ON cases and 202 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 34338585 |
| Year | 2021 |
| Title | Association of RAGE rs1800624 and rs1800625 gene polymorphisms with predisposition to optic neuritis and optic neuritis together with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Results indicate that rs1800624 polymorphism is not statistically significant in optic neuritis manifestation |
| Mechanism/Pathway | the RAGE gene was selected as it is a part of the inflammation process |
