Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | genotype |
| refSNP ID | DR8 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood leukocytes |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Japanese |
| Sample Size | 44 MS patients and 98 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1286977 |
| Year | 1992 |
| Title | HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Frequencies of HLA-A, B, C in 44 MS patients and 98 controls |
| Mechanism/Pathway | These results suggest that MS susceptibility may result from polygenic influences and from the presence of environmental factors. |
