Basic information of NFKB1 :
| Official Symbol of Gene | NFKB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 7794 |
| Official Full Name | nuclear factor kappa B subunit 1 |
| Also known as | KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000109320 MIM:164011; AllianceGenome:HGNC:7794 |
| Map Location | 4q24 |
| Variation Type | Gene polymorphisms |
| refSNP ID | -94 ins/del ATTG promoter polymorphism |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iranian population |
| Sample Size | 200 MS cases and 200 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23618653 |
| Year | 2013 |
| Title | Relationship between NF-κB1 -94 ins/del ATTG polymorphism and susceptibility of multiple sclerosis in Iranian MS patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | our study showed no association between -94 ins/del ATTG polymorphism and risk of multiple sclerosis in Iranian patients |
| Mechanism/Pathway | NF-κB1 is one of the most important molecules which regulates the immune functions |
