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Basic information of IL2 :

Official Symbol of Gene IL2
Species Homo sapiens
Entrez Gene ID 6001
Official Full Name interleukin 2
Also known as IL-2; TCGF; lymphokine
Gene Type protein coding
dbXrefs Ensembl:ENSG00000109471 MIM:147680; AllianceGenome:HGNC:6001
Map Location 4q27
Variation Type polymorphisms
refSNP ID The positionβ384 in the promoter region

Sample information of multiple sclerosis:

Detected Sample venous blood
Sample Detail N/A
Detected Method PCR – RFLP
Disease MS
Disease subtype RRMS、SPMS
Population Japanese population
Sample Size 113 patients/118 controls

Literature information of multiple sclerosis :

Pubmed ID 12409183
Year 2002
Title An assessment of the association between IL-2 gene polymorphisms and Japanese patients with multiple sclerosis.

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result Our results showed no significant differences in the distribution of the two polymorphisms between MS patients and controls. Furthermore,no association was observed between IL-2 gene polymorphisms and clinical characteristics
Mechanism/Pathway no functional significance