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Basic information of TRIOBP :

Official Symbol of Gene TRIOBP
Species Homo sapiens
Entrez Gene ID 11078
Official Full Name TRIO and F-actin binding protein
Also known as TARA; TAP68; DFNB28; dJ37E16.4; HRIHFB2122
Gene Type protein coding
dbXrefs Ensembl:ENSG00000100106 MIM:609761; AllianceGenome:HGNC:17009
Map Location 22q13.1
Variation Type SNP
refSNP ID rs201693690

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail NA
Detected Method PCR
Disease MS
Disease subtype MS
Population Chinese
Sample Size 8MS/26Control

Literature information of multiple sclerosis :

Pubmed ID 30140248
Year 2018
Title Novel Variants Identified in Multiple Sclerosis Patients From Southern China

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result MS in southern China may have association with unique genetic variants,our data suggest TRIOBP as a potential novel risk gene.
Mechanism/Pathway Multiple sclerosis (MS) is an autoimmune and demyelinating disease.Genome-wide association studies have shown that MS is associated with many genetic variants in some human leucocyte antigen genes and other immune-related genes,however, those studies were mostly specific to Caucasian populations.