Basic information of FCGR2A :
| Official Symbol of Gene | FCGR2A |
| Species | Homo sapiens |
| Entrez Gene ID | 2212 |
| Official Full Name | Fc gamma receptor IIa |
| Also known as | CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1; FcgammaRIIa |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000143226 MIM:146790; AllianceGenome:HGNC:3616 |
| Map Location | 1q23.3 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | southern Iran. |
| Sample Size | 136MS/136Control |
Literature information of multiple sclerosis :
| Pubmed ID | 18698123 |
| Year | 2006 |
| Title | Investigation of Fcgamma RIIA and Fcgamma RIIIA Polymorphism in Multiple Sclerosis: A Case Control Study |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The results of the present study add the FcgammaRIIA gene to the gene networks which determine the severity of MS in southern Iran. |
| Mechanism/Pathway | Receptors for the Fc fragment of IgG (FcgammaR) might induce inflammatory responses through linking the humoral and cellular immune responses by targeting immune complexes to effector cells. |
