Basic information of CNR1 :
| Official Symbol of Gene | CNR1 |
| Species | Homo sapiens |
| Entrez Gene ID | 1268 |
| Official Full Name | cannabinoid receptor 1 |
| Also known as | CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000118432 MIM:114610; AllianceGenome:HGNC:2159 |
| Map Location | 6q15 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | NA |
| Sample Size | 30RRMS |
Literature information of multiple sclerosis :
| Pubmed ID | 25520956 |
| Year | 2014 |
| Title | CB1 receptor affects cortical plasticity and response to physiotherapy in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Positive |
| Result | Our results provide the first evidence that genetic differences within the CB1R may influence clinical responses to exercise therapy, and they strengthen the hypothesis that CB1Rs are involved in the regulation of synaptic plasticity and in the control of spasticity in humans. |
| Mechanism/Pathway | Therapeutic effects of physical therapy in neurologic disorders mostly rely on the promotion of use-dependent synaptic plasticity in damaged neuronal circuits. |
