Basic information of CYP24A1 :
| Official Symbol of Gene | CYP24A1 |
| Species | Homo sapiens |
| Entrez Gene ID | 1591 |
| Official Full Name | cytochrome P450 family 24 subfamily A member 1 |
| Also known as | CP24; HCAI; CYP24; HCINF1; P450-CC24 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000019186 MIM:126065; AllianceGenome:HGNC:2602 |
| Map Location | 20q13.2 |
| Variation Type | SNP |
| refSNP ID | rs2248359 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | Iranian population |
| Sample Size | 82 with MS and 100 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 36381285 |
| Year | 2022 |
| Title | The HLA rs9267649 and CYP24A1 rs2248359 Variants are Associated with Multiple Sclerosis: A Study on Iranian Population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The present research results provide further evidence on the association of the two variants rs9267649 of the HLA and rs2248359 of the CYP24A1 gene with MS etiology and an increased risk of MS in Iranian RRMS patients. |
| Mechanism/Pathway | Studies have shown that MS results from synergism between genetic and environmental factors. |
