Basic information of CD24 :
| Official Symbol of Gene | CD24 |
| Species | Homo sapiens |
| Entrez Gene ID | 100133941 |
| Official Full Name | CD24 molecule |
| Also known as | CD24A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000272398 MIM:600074; AllianceGenome:HGNC:1645 |
| Map Location | 6q21 |
| Variation Type | SNP |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Among the 242 MS samples, 233 were Caucasian, 7 were African-American, 1 was Hispanic, and 1 was Asian |
| Sample Size | 242 patients/256 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 14657362 |
| Year | 2003 |
| Title | CD24 is a genetic modifier for risk and progression of multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We found that the CD24v/v renders a >2-fold increase in the relative risk of MS in the general population |
| Mechanism/Pathway | . Thus, CD24 polymorphism is a genetic modifier for susceptibility and progression of MS in the central Ohio cohort that we studied, perhaps by affecting the efficiency of CD24 expression on the cell surface |
