Basic information of TRBV20OR9-2 :
| Official Symbol of Gene | TRBV20OR9-2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6962 |
| Official Full Name | T cell receptor beta variable 20/OR9-2 (non-functional) |
| Also known as | TCR; TRB; CDR3; TCRB; TCRBV2O; TCRBV20S2; TCRBV2S2O |
| Gene Type | pseudo |
| dbXrefs | Ensembl:ENSG00000205274 IMGT/GENE-DB:TRBV20/OR9-2; AllianceGenome:HGNC:12197 |
| Map Location | 9p13.3 |
| Variation Type | restriction fragments length polymorphisms (RFLP) |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS/CPMS |
| Population | Caucasian Spaniards. |
| Sample Size | 97 patients/93controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8104194 |
| Year | 1993 |
| Title | The germline repertoire of T cell receptor beta-chain genes in multiple sclerosis patients from Spain |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Our data suggest that the TcR/3 chain gene complex contains one or more genes involved in genetic susceptibility to develop MS |
| Mechanism/Pathway | We found the distribution of the TcR haplotypes defined by the alleles of the three loci studied in the MS patients was significantly different from that found in control individuals. The distribution of TcR haplotypes in R / R MS patients was also different from that observed in controls. |
