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Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type Alleles
refSNP ID NA

Sample information of multiple sclerosis:

Detected Sample CSF
Sample Detail NA
Detected Method PCR
Disease MS
Disease subtype RRMS/PCPMS
Population NA
Sample Size 26 PCPMS/74RRMS

Literature information of multiple sclerosis :

Pubmed ID 2571150
Year 1989
Title Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result Both clinical forms of MS were found to be associated with the DRw15,DQw6 haplotpe.
Mechanism/Pathway Both clinical forms of MS were found to be associated with the DRw15,DQw6 haplotpe.