Basic information of HLA-DQB2 :
| Official Symbol of Gene | HLA-DQB2 |
| Species | Homo sapiens |
| Entrez Gene ID | 3120 |
| Official Full Name | major histocompatibility complex, class II, DQ beta 2 |
| Also known as | DQB2; HLA-DXB; HLA-DQB1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000232629 MIM:615161; AllianceGenome:HGNC:4945 |
| Map Location | 6p21.32 |
| Variation Type | Alleles |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | CSF |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS/PCPMS |
| Population | NA |
| Sample Size | 26 PCPMS/74RRMS |
Literature information of multiple sclerosis :
| Pubmed ID | 2571150 |
| Year | 1989 |
| Title | Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | In addition, primarily chronic pro-gressive MS was positively associated with theDQBl restriction fragment pattern seen in DR4,DQw8, DR7,DQw9, and DRw8, DQw4 haplotypes, as well as negatively associated with the Taq I DQBI allelic pattern corresponding to the serological specificity DQw7. |
| Mechanism/Pathway | In addition, primarily chronic pro-gressive MS was positively associated with theDQBl restriction fragment pattern seen in DR4,DQw8, DR7,DQw9, and DRw8, DQw4 haplotypes, as well as negatively associated with the Taq I DQBI allelic pattern corresponding to the serological specificity DQw7. |
