Basic information of IL1RN :
| Official Symbol of Gene | IL1RN |
| Species | Homo sapiens |
| Entrez Gene ID | 3557 |
| Official Full Name | interleukin 1 receptor antagonist |
| Also known as | DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136689 MIM:147679; AllianceGenome:HGNC:6000 |
| Map Location | 2q14.1 |
| Variation Type | Alleles |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | NA |
| Sample Size | 57 patients/65ontrols |
Literature information of multiple sclerosis :
| Pubmed ID | 7564774 |
| Year | 1995 |
| Title | Interleukin-1 receptor antagonist gene polymorphism and multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Our results are the first to implicate the IL-lra gene in susceptibility to multiple sclerosis. |
| Mechanism/Pathway | DNA within the second intron of the IL-lra gene, which contains variable numbers of an identical repeat of 86 base-pairs, was amplified by PCR (details available from authors). |
