Basic information of Mbp :
| Official Symbol of Gene | Mbp |
| Species | Mus musculus |
| Entrez Gene ID | 17196 |
| Official Full Name | myelin basic protein |
| Also known as | NA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000041607 AllianceGenome:MGI:96925 |
| Map Location | 18 E3; 18 55.84 cM |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | NA |
| Sample Size | N=6-8mice |
Literature information of multiple sclerosis :
| Pubmed ID | 9209515 |
| Year | 1997 |
| Title | Major histocompatibility complex-controlled protective influences on experimental autoimmune encephalomyelitis are peptide specific |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We conclude that both MHC-controlled promoting and protective influences on EAE are dependent on certain MHC/MBP peptide combinations, and that the 87-110 region of MBP contains a major MHC-associated encephalitogenic epitope in the rat. |
| Mechanism/Pathway | The myelin basic protein (MBP) peptide 63-88-induced experimental autoimmune encephalomyelitis (EAE) and its associated T cell cytokine profile are influenced by the rat major histocompatibility complex (MHC). |
