Basic information of CYP2D6 :
| Official Symbol of Gene | CYP2D6 |
| Species | Homo sapiens |
| Entrez Gene ID | 1565 |
| Official Full Name | cytochrome P450 family 2 subfamily D member 6 |
| Also known as | CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000100197 MIM:124030; AllianceGenome:HGNC:2625 |
| Map Location | 22q13.2 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | NA |
| Population | Spanish individuals |
| Sample Size | 118 patients/200controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8750111 |
| Year | 1995 |
| Title | Frequency of CYP2D6 allelic variants in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | These results indicate that mutations at the CYP2D6 gene do 1 not seem to be a factor in determining susceptibility to MS |
| Mechanism/Pathway | Recent reports have shown association between CYP2D6 polymorphism and neuronal degenerative diseases such as Parkinson's disease. |
