Basic information of CCR5 :
| Official Symbol of Gene | CCR5 |
| Species | Homo sapiens |
| Entrez Gene ID | 1234 |
| Official Full Name | C-C motif chemokine receptor 5 |
| Also known as | CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000160791 MIM:601373; AllianceGenome:HGNC:1606 |
| Map Location | 3p21.31 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS/PPMS/SPMS |
| Population | Northern Ireland |
| Sample Size | 439MS/230Health |
Literature information of multiple sclerosis :
| Pubmed ID | 15124759 |
| Year | 2004 |
| Title |
In |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | These results suggest that the C C R5 d32 polymorphism is no t a major deter minant o f susceptibility to develop MS in the populatio n under study, and co nflict with a previo usly repo rted associatio n betw een C C R5 d32 carriage and a better prognosis |
| Mechanism/Pathway |
The C C R5 chemo kine recepto r has been implicated in the patho genesis of multiple sclerosis (MS). We carried out an allelic association study using a deletio n polymo rphism in the coding regio n o f the C C R5 gene in 331 relapsing |
