Basic information of CD1E :
| Official Symbol of Gene | CD1E |
| Species | Homo sapiens |
| Entrez Gene ID | 913 |
| Official Full Name | CD1e molecule |
| Also known as | R2; CD1A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000158488 MIM:188411; AllianceGenome:HGNC:1638 |
| Map Location | 1q23.1 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS/PPMS/SPMS |
| Population | NA |
| Sample Size | 205MS/223Health |
Literature information of multiple sclerosis :
| Pubmed ID | 21496400 |
| Year | 2011 |
| Title | CDIAAND CDIE GENE POLYMORPHISMS ARE ASSOCIATED WITH SUSCEPTIBILITY TO MULTIPLE SCLEROSIS |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | CDIE 01-01 is associated with a reduced risk ofMS (OR 0.54, p=O.OOI); CDIA 02-02 (OR 1.99, p=0.012) or CDIE 02-02 (OR 2.45, p=O.OOO) with an increased risk. |
| Mechanism/Pathway | Multiple sclerosis (MS) is thought to be an autoimmune T-cell-mediated disease directed at myelin antigens of the central nervous system. |
