Basic information of CXCL16 :
| Official Symbol of Gene | CXCL16 |
| Species | Homo sapiens |
| Entrez Gene ID | 58191 |
| Official Full Name | C-X-C motif chemokine ligand 16 |
| Also known as | SRPSOX; CXCLG16; SR-PSOX |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000161921 MIM:605398; AllianceGenome:HGNC:16642 |
| Map Location | 17p13.2 |
| Variation Type | Allele |
| refSNP ID | NA |
Sample information of multiple sclerosis:
| Detected Sample | PBMC |
| Sample Detail | NA |
| Detected Method | Real-Time PCR |
| Disease | MS |
| Disease subtype | RRMS/PPMS/SPMS |
| Population | NA |
| Sample Size | 459MS/303Health |
Literature information of multiple sclerosis :
| Pubmed ID | 24854635 |
| Year | 2014 |
| Title | The interferon-induced helicase C domain-containing protein 1 gene variant (rs1990760) as an autoimmune-based pathology susceptibility factor |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The main finding of this study is gender-specific association of CXCL16 A181V polymorphism with susceptibility to MS in females. |
| Mechanism/Pathway | CXC ligand 16 (CXCL16) is a multifunctional chemokine involved in cell adhesion and chemoattraction as well as in the scavenging of oxidized lipoproteins.Experimental data suggest the roles of CXCL16 in patho-genesis of multiple sclerosis (MS) |
